Xylazine Bill Protects Veterinary Access to the Popular Sedative
Xylazine is an important animal sedative that's used in almost every sector of veterinary medicine. However, illicit or illegal xylazine is increasingly showing up in street drugs.
Legislation proposed earlier this year and supported by the American Veterinary Medical Association (AVMA) and American Association of Bovine Practitioners (AABP) would help combat the emerging threat posed by illicit xylazine while protecting veterinarians’ ability to legitimately use the product.
"We don’t use much xylazine in pigs as we don’t do much anesthesia," says Jim Lowe, DVM, associate dean of Online Programs and Extension at the University of Illinois College of Veterinary Medicine. "But it is an issue for vets in general as DEA schedule drugs are a huge hassle and really limit access. It is one more limit on what we can do."
Combating Illicit Use of Xylazine
Xylazine, also known as “tranq,” is being used as a low-cost drug cutting agent. The Drug Enforcement Agency (DEA) reported 23% of fentanyl powder contained it in 2022. In humans, the product can cause depressed breathing and heart rate, unconsciousness, necrosis, and even death. Naloxone does not reverse the effects of xylazine because it is not an opioid.
The Combating Illicit Xylazine Act (S. 993/H.R. 1839) – a bipartisan bill that the AVMA helped develop, introduce, and build bipartisan support for – was introduced to Congress in March. The Biden administration designated fentanyl combined with xylazine as an “emerging threat” to the U.S. in April.
The designation allows the federal government to put together resources to counteract the illegal supply of the drug combination found nationwide, according to a press release from the Biden administration.
It’s the first time the United States has declared a drug an emerging threat, a category enabled by a 2018 federal bill, said Rahul Gupta, M.D., director of the Office of National Drug Control Policy (ONDCP), in the release.
Illicit xylazine’s growing role in being sold illegally and overdose deaths nationwide prompted the White House to make this designation.
Schedule III Designation Would Help
If the proposed legislation becomes law, it will make the manufacturing, distribution, dispensing, or possession of illicit xylazine for trafficking subject to Schedule III penalties under the federal Controlled Substances Act, the AVMA reports.
Illicit use of xylazine includes any use, or intended use, in people and would address any diversion of xylazine from veterinary sources. At the same time, the legitimate uses mean xylazine would remain an FDA-regulated, prescription veterinary drug.
A call to action urging veterinary advocates to reach out to their members of Congress in support of the legislation was recently featured by the AVMA’s Congressional Advocacy Network.