Aptimmune Launches Industry’s First Inactivated Mucosal Influenza A Virus Vaccine in Swine (IAV-S)
Aptimmune Biologics introduces the industry’s first inactivated mucosal influenza A virus in swine (IAV-S) vaccine administered via nasal spray. Aptimmune’s IAV-S vaccine utilizes the BARRICADE proprietary vaccine formulation that gives swine producers and veterinarians a completely different approach to conventional inactivated injectable and live virus vaccines for safely preventing and managing respiratory disease.
This inactivated mucosal vaccine is a new class of vaccines that mitigates respiratory disease at the point of entry. BARRICADE IAV-S combines three core components essential for effective disease protection: First, contemporary influenza type A antigen relevant for current application. Second, a powerful and safe immune-stimulating adjuvant. Lastly, Aptimmune’s proprietary nanoparticles deliver the vaccine payload to immune cells at the mucosal surface.
“This inactivated-virus mucosal vaccine with its needleless, intranasal administration is safe to pigs, people, and is PQA-Plus friendly, making it an effective alternative to conventional IAV-S vaccines,” says Jessica Seate, DVM, professional services veterinarian for Aptimmune Biologics.
BARRICADE IAV-S is the second intranasally administered mucosal swine vaccine product introduced by Aptimmune this year, says Aaron Gilbertie, Aptimmune CEO. “Our BARRICADE PRRS vaccine continues to perform well on swine farms across the country, under some of the toughest disease conditions, and has validated our collaborative innovation model for developing and manufacturing custom mucosal vaccines. And because our PRRS and IAV-S vaccines utilize the same technology, they can be combined and administered together to prevent these two important diseases when appropriate.”
The product is available in 250-mL and 500-mL bottles. The company recommends pigs be vaccinated intranasally once at 7-10 days of age and again at weaning (approximately 3-4 weeks of age). Aptimmune’s IAV-S vaccine formulated with BARRICADE™ technology includes a 21-day withdrawal period, the shortest allowed for custom vaccines.
For more information, contact your swine veterinarian or visit aptimmune.com.
Bavaria Corporation Offers Natural Antimicrobial
Organosulphured compounds in plants in the Allium family, such as garlic and onions, have natural antimicrobial activity that provides benefits comparable to antibiotics. Bavaria’s new product, GOL, is a standardized and stabilized pool of these organosulphured molecules. Added to feed or water, GOL improves intestinal health, helps maintain feed consumption and reduces diarrhea during infectious events.
GOL also aids in controlling Coccidiosis and increases transference of immunoglobulin G from parent to offspring thus maintaining overall health, increasing weight gain and lowering veterinary expenses.
GOL’s mode of action is through thiosulphnates that are the most active of the organosulphured compounds found in Allium plants. These small molecules are very reactive and have a high affinity for enzymes that affect cell membrane integrity, especially Cystein proteinases. This mechanism explains why thiosulphnates are effective in controlling parasites, fungi and bacteria.
Effective at low dosage rates, GOL provides an economical and natural alternative to antibiotics for swine, ruminants and poultry. Several formulations are available including liquid for drinking water, powder for mash and granulated feed, microencapsulated powder for extruded feed and liofilizated (freeze dried) for ruminants and horses.
For more information, go to http://www.bavariacorp.com/